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CELOPRE® LS22

CELOPRE® LS22
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CELOPRE® LS22 is a USP/NF pharmacopoeia grade, 7.0–9.9% hydroxypropoxylated, moderately substituted HPMC, mainly used for pharmaceutical film coating and tablet bonding. It has both film-forming and lightweight structure capabilities, and is suitable for immediate-release systems and direct compression processes.

Test Item Unit Specification Method
Appearance White to Yellowish white Visual
Identification A Conforms USP30 NF25
Identification B Conforms USP30 NF25
Identification C Conforms USP30 NF25
pH 5.0-7.5 USP30 NF25
Loss on drying % 5.0 Max USP30 NF25
Residue on ignition % 0.5 Max USP30 NF25
Chloride % Not more than 0.36 USP30 NF25
Heavy metals % Not more than 0.001 USP30 NF25
Hydroxypropoxyl Content % 7.0 – 9.9 USP30 NF25
Particle size: Retain on 106m Micro 1.0 Max
Pass through 75m Micron 90 Min.

Remark: This product complies with the specifications described in the current pharmacopeia.

Package

Pack in drums, net weight 25kg per drum.

Storage

Store in sealed container, keep away from sunlight & moisture.

Multi-Purpose Pharmaceutical HPMC CELOPRE® LS22 Applications

  • Pharmaceutical Film Coating

    Pharmaceutical Film Coating

    CELOPRE® LS22 is suitable for tablet coating, taste masking, and appearance improvement. Compared to low-viscosity HPMC, it features a thicker film and greater abrasion resistance.

    Advantages

    • Thicker film formation, providing better coating coverage and protection
    • Greater abrasion resistance, enhancing the coating layer’s resistance to mechanical damage
    • Effective taste masking, improving the medication experience
    • Improved tablet appearance smoothness and overall texture
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  • Tablet Binder

    Tablet Binder

    CELOPRE® LS22 is suitable for both wet granulation and direct compression, to improve tablet hardness and compression performance.

    Advantages

    • Significantly improves tablet hardness and enhances mechanical strength
    • Improves tablet formability and reduces the risk of tablet breakage
    • Suitable for both wet granulation and direct compression processes
    • Suitable for high drug loading or difficult-to-formulate formulations
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  • Immediate-release Tablets (IR)

    Immediate-release Tablets (IR)

    CELOPRE® LS22 can be used for disintegration regulation and API dispersion.

    Advantages

    • Regulates disintegration behavior to support rapid release requirements
    • Promotes uniform API dispersion, ensuring content uniformity
    • Compatible with immediate-release tablet granulation and tableting processes
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