CELOPRE® LS22 is a USP/NF pharmacopoeia grade, 7.0–9.9% hydroxypropoxylated, moderately substituted HPMC, mainly used for pharmaceutical film coating and tablet bonding. It has both film-forming and lightweight structure capabilities, and is suitable for immediate-release systems and direct compression processes.
| Test Item | Unit | Specification | Method |
|---|---|---|---|
| Appearance | White to Yellowish white | Visual | |
| Identification A | Conforms | USP30 NF25 | |
| Identification B | Conforms | USP30 NF25 | |
| Identification C | Conforms | USP30 NF25 | |
| pH | 5.0-7.5 | USP30 NF25 | |
| Loss on drying | % | 5.0 Max | USP30 NF25 |
| Residue on ignition | % | 0.5 Max | USP30 NF25 |
| Chloride | % | Not more than 0.36 | USP30 NF25 |
| Heavy metals | % | Not more than 0.001 | USP30 NF25 |
| Hydroxypropoxyl Content | % | 7.0 – 9.9 | USP30 NF25 |
| Particle size: Retain on 106m | Micro | 1.0 Max | |
| Pass through 75m | Micron | 90 Min. |
Remark: This product complies with the specifications described in the current pharmacopeia.
Pack in drums, net weight 25kg per drum.
Store in sealed container, keep away from sunlight & moisture.
CELOPRE® LS22 is suitable for tablet coating, taste masking, and appearance improvement. Compared to low-viscosity HPMC, it features a thicker film and greater abrasion resistance.
CELOPRE® LS22 is suitable for both wet granulation and direct compression, to improve tablet hardness and compression performance.
CELOPRE® LS22 can be used for disintegration regulation and API dispersion.
