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CELOPRE® MF50

CELOPRE® MF50
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Test Item Unit Specification Standard
Appearance White to Yellowish white Visual
Characters Conforms EP
Identification A Conforms EP/USP
Identification B Conforms EP/USP
Identification C Conforms EP/USP
Identification D Conforms EP
Identification E Conforms EP
Identification F Conforms EP
pH 5.5-8.0 EP/USP
Apparent Viscosity mPa.s 40.0 – 60.0 EP/USP
Appearance of Solution Conforms EP
Chlorides % Max 0.5 EP
Loss on Drying % 5.0 Max EP/USP
Residue on Ignition % 1.0/1.5 Max EP/USP
Heavy Metals % Not more than 0.001 EP/USP
Arsenic ppm 3.0 Max USP
Methoxyl Content % 27.0 – 30.0 USP
Hydroxypropoxyl Content % 4.0 – 7.5 USP
Total Microbial Count cfu/g Max 1000
Total Mould and Yeast cfu/g Max 100
E.Coli Negative

 

CELOPRE® MF50 USP/EP Pharmaceutical HPMC

CELOPRE® MF50 is a low-hydroxypropoxy grade of HPMC (Grade E3), characterized by reduced hydrophilicity, a relatively slower dissolution rate, an elevated thermal gelation temperature, and film-forming properties that tend to be brittle and rigid.

  • Pharmaceutical Film Coatings

    Pharmaceutical Film Coatings

    CELOPRE® MF50 is specifically designed to meet the protective requirements of pharmaceutical film coatings; it is particularly well-suited for moisture-barrier coatings, high-strength coatings, and coating layers requiring environmental stability.

    Compared to high-hydroxypropoxy versions, it forms a denser film with superior moisture resistance, prioritizing protective functionality over mere aesthetic enhancement.

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  • Tablet Formation

    Tablet Formation

    CELOPRE® MF50 is particularly well-suited for tablet formation, serving as a binder for both dry and wet granulation processes, as well as a structural aid for tablets.

    Its key advantage lies in its low hydroxypropoxy content; this structural feature presents stronger intermolecular forces and slightly enhanced structural integrity, thereby contributing to improved tablet formability.

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  • Cosmetic Formulations

    Cosmetic Formulations

    CELOPRE® MF50 is suitable for use in cosmetic formulations—specifically styling and oil-control products.

    It forms a dry film with a slightly firm tactile feel; while not as smooth as the high-hydroxypropoxy version, it is ideally suited for applications where a non-sticky finish, oil control, or styling performance is desired.

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