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Celopre® ME4M

Celopre® ME4M
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Test Item Unit Specification Standard
Appearance White to Yellowish white Visual
Characters Conforms EP
Identification A Conforms EP/USP
Identification B Conforms EP/USP
Identification C Conforms EP/USP
Identification D Conforms EP
Identification E Conforms EP
Identification F Conforms EP
pH 5.5-8.0 EP/USP
Apparent Viscosity mPa.s 3,000 – 5,000 EP/USP
Appearance of Solution Conforms EP
Chlorides % Max 0.5 EP
Loss on Drying % 5.0 Max EP/USP
Residue on Ignition % 1.0/1.5 Max EP/USP
Heavy Metals % Not more than 0.001 EP/USP
Arsenic ppm 3.0 Max USP
Methoxyl Content % 28.0 – 30.0 USP
Hydroxypropoxyl Content % 7.5 – 12.0 USP
Total Microbial Count cfu/g Max 1000
Total Mould and Yeast cfu/g Max 100
E.Coli Negative

 

Celopre® ME4M Applications

Pharmaceutical excipient grade HPMC (tablet / capsule / controlled release grade).

  • Tablet Systems

    Tablet Systems

    Celopre® ME4M is suitable for use in tablet systems as a direct compression binder, a sustained-release matrix material, and a film-coating agent; it represents the typical viscosity grade selected for sustained-release (SR/CR) tablets and controlled-release matrix systems.

    Advantages:

    • Direct Compression Binder: Exhibits excellent compressibility and formability.
    • Sustained-Release Matrix Material: Enables controlled drug release.
    • Film-Coating Compatibility: Process-friendly and well-suited for film coating applications.
    • Typical Application: Used in SR/CR controlled-release matrix systems.
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  • Cosmetics Industry

    Cosmetics Industry

    Celopre® ME4M serves as a film-forming agent for face masks, a thickening and stabilizing agent for emulsions, a structural agent for gel systems, and an anti-settling stabilizer, thereby meeting a wide range of formulation requirements.

    Advantages:

    • Excellent film-forming properties for face masks, offering a comfortable skin feel
    • Provides effective thickening and stabilization for emulsions, ensuring a uniform texture
    • Creates clear, well-defined gel structures with a pleasant tactile sensation
    • Offers superior anti-settling performance, enhancing overall product stability
    • Compatible with a diverse range of cosmetic formulation systems
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  • Laboratory & Pharmaceutical R&D

    Laboratory & Pharmaceutical R&D

    Celopre® ME4M can be applied to studies involving controlled-release models, granulation processes, and viscosity modulation systems, thereby meeting the diverse formulation exploration needs typical of the laboratory research phase.

    Advantages:

    • Controlled-Release Model Studies: Controllable release behavior with excellent data reproducibility.
    • Granulation Studies: Moderate binding strength resulting in superior granule uniformity.
    • Viscosity Modulation Systems: Well-defined viscosity range facilitating process optimization.
    • Adaptability to R&D Scenarios: Wide operating window offering high flexibility.
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