CELOPRE® MK30M

CELOPRE® MK30M is primarily utilized in 12-hour and 24-hour sustained-release tablets, as well as controlled-release matrix tablets.

It is particularly well-suited for formulations containing highly soluble APIs and preparations requiring strictly defined release profiles to prevent dose dumping.

Its key advantage is construction of a highly stable hydrophilic gel matrix, which enables the precise modulation of drug diffusion rates, effectively prevents burst release, and ensures a smooth, sustained release profile.

CELOPRE® MK30M is specifically designed for  a high API content where standard HPMC struggles to maintain structural integrity.

Advantages

• Maintains tablet structural integrity even at high drug-loading levels
• Prevents excessively rapid or uncontrolled drug release
• Suitable for formulations with a high API-to-excipient ratio—a challenge typically beyond the capabilities of standard HPMC
• Balances structural strength with consistent, controlled-release performance

This product is suitable for multi-layer tablets (bi-layer tablets), gradient release formulations, and combination controlled-release systems.

Advantages

• Supports multi-layer tablet structures, enabling the design-based separation of different drugs or release phases.
• Facilitates the construction of gradient release profiles to meet individualized drug delivery requirements.
• Applicable to combination controlled-release systems, offering compatibility with a variety of release mechanisms.
• Maintains matrix stability, ensuring controlled release even within complex structural configurations.